Hepatotoxicity and nephrotoxicity of 3-bromopyruvate in mice
نویسندگان
چکیده
منابع مشابه
Hepatotoxicity and nephrotoxicity of 3-bromopyruvate in mice.
PURPOSE: To investigate the hepatotoxicity and nephrotoxicity of 3-Bromopyruvate (3BP) in mice. METHODS: Fifteen nude mice were grafted subcutaneously in the left flank with MDA-MB-231 cells, then all mice were divided into control group (PBS), 3BP group (8 mg/kg), positive group (DNR: 0.8 mg/kg) when tumor volume reached approximately 100 mm3. 28 days later, tumors, livers and kidneys were s...
متن کاملCurative effects of Cassia fistula fruit extract on bromobenzene-induced hepatotoxicity and nephrotoxicity in mice
Background & objectives: The present investigation was designed to evaluate the post-treatment properties of the hydroalcoholic fruit extract of cassia fistula (golden shower tree) in male Albino mice. Materials & Methods: Biomarkers and histological liver and kidney alterations, aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (...
متن کاملcurative effects of cassia fistula fruit extract on bromobenzene-induced hepatotoxicity and nephrotoxicity in mice
background & objectives: the present investigation was designed to evaluate the post-treatment properties of the hydroalcoholic fruit extract of cassia fistula (golden shower tree) in male albino mice. materials & methods: biomarkers and histological liver and kidney alterations, aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), γ-glutamyl tra...
متن کاملDamascenine induced hepatotoxicity and nephrotoxicity in mice and in vitro assessed human erythrocyte toxicity
Nigella damascena seed is characterized by the presence of the major alkaloid, damascenine and its related metabolites. To our knowledge, no detailed subchronic toxicological assessment of damascenine (DA) has been reported. The present study evaluated the potential toxicity of DA in vivo after sub-chronic intraperitoneal (i.p) administration in mice and in vitro following human erythrocyte hem...
متن کاملNephrotoxicity and hepatotoxicity evaluation of Crocus sativus stigmas in neonates of nursing mice.
BACKGROUND Crocus sativus, known as saffron crocus, is best known for the spice saffron. Saffron use spans more than 3500 years, however, its toxicity on neonates during lactation has not yet evaluated. OBJECTIVES This study was aimed to examine the acute toxicity of saffron on adult mice and its nephrotoxicity and hepatotoxicity on neonates of lactating mothers that used saffron during lacta...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Cirurgica Brasileira
سال: 2016
ISSN: 0102-8650
DOI: 10.1590/s0102-865020160110000004